EFFICACY OF UNRIPE Musa sapientum WHOLE FRUIT ON NEUROMUSCULAR STRENGTH AND OLFACTORY RESPONSE LINKED TO CEREBRO-CEREBELLAR IONIZED CALCIUM, MUSCLE CREATINE KINASE AND PLASMA ACETYLCHOLINESTERASE

Main Article Content

O. N. ILOCHI
A. N. CHUEMERE

Abstract

The performance of daily activities is dependent on several factors, such as strength, balance, flexibility, endurance and perception of sensations of special senses. Unripe Musa sapientum is one of the most cultivated tropical fruit in the world, with scarce literature concerning its neurologic relevance. This study determined the tendency for Unripe Musa sapientum whole fruit hydromethanolic extract to influence neuromuscular strength, endurance and olfaction in normal condition. Peak absorbance was read at 200 to 1100 nm using ultraviolet visible spectrophotometry to determine some bioactive functional groups in unripe Musa sapientum whole fruit extract. The test groups ii-iv were orally subjected to graded doses of unripe Musa sapientum whole fruit; 100, 150 and 200 mg/kg respectively, all compared to control group i. There was a significant dose-dependent improvement in olfactory response, neuromuscular strength and endurance. Unripe Musa sapientum extract caused a dose-dependent significant decrease in plasma creatine kinase but increased acetylcholinesterase and ionized calcium in cerebral cortex and cerebellum. The effectiveness of the extract on the tested parameters was progressive and its efficacy may be dose-dependent.

Keywords:
Muscle, olfaction, performance, M. sapientum, calcium

Article Details

How to Cite
ILOCHI, O. N., & CHUEMERE, A. N. (2021). EFFICACY OF UNRIPE Musa sapientum WHOLE FRUIT ON NEUROMUSCULAR STRENGTH AND OLFACTORY RESPONSE LINKED TO CEREBRO-CEREBELLAR IONIZED CALCIUM, MUSCLE CREATINE KINASE AND PLASMA ACETYLCHOLINESTERASE. Asian Journal of Advances in Medical Science, 3(4), 222-231. Retrieved from http://mbimph.com/index.php/AJOAIMS/article/view/2578
Section
Original Research Article

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