Main Article Content
There was a significant lack of knowledge about pathology, transmission method, epidemiology and management of the novel coronavirus (severe acute respiratory syndrome coronavirus 2 or SARS-CoV-2) pneumonia or coronavirus disease 2019 (COVID-19). Comparison of the genome sequences of SARS-CoV-2, SARS-CoV and Middle East Respiratory Syndrome coronavirus (MERS-CoV) showed that SARS-CoV-2 had some different sequence. Major symptoms showed in COVID-19 were like severe pneumonia disease such as fever, cough and respiratory problems that were similar symptoms to SARSCoV. The aim of this study was to have a preliminary concepts about the taxonomy, morphology and genome of its pathogen. This study was also focused to find the ways of management, treatment, as well as prevention of COVID-19 or Global disaster in 2020. Isolation of cases, home quarantine, hygienic habits and social distancing were recommended to check human to human transmission. Antivirals drugs, anticoagulant therapy, use of serum of recovered persons from this disease and development of vaccine were under investigation.
Khot WY, Milind Y, Nadkar MY. The 2019 novel coronavirus outbreak – A global threat. Journal of the Association of Physicians of India. 2020;68:67-71.
Zhu N, Zhang D, Wang W, Li X, Yang B, Song J, et al. A novel coronavirus from patients with pneumonia in China, 2019. N. Engl J. Med.; 2020.
Chan JF, Kok KH, Zhu Z, Chu H, To KK, Yuan S, Yuen KY. Genomic characterization of the 2019 novel human-pathogenic coronavirus isolated from a patient with atypical pneumonia after visiting Wuhan. Emerg Microbes Infect. 2020;9(1):221- 236.
Chen Y, Liu Q, Guo D. Emerging coronaviruses: Genome structure, replication and pathogenesis. J. Med. Virol. 2020;92(4): 418-423.
Kannan S, Ali PSS, Sheeza A, Hemalatha K. COVID-19 (Novel Coronavirus 2019) – Recent trends. SARS European Review for Medical and Pharmacological Sciences. 2020;24:2006-2011.
Wu F, Zhao S, Yu B, Chen YM, Wang W, Hu Y. Complete genome characterisation of a novel coronavirus associated with severe human respiratory disease in Wuhan, China. bioRxiv; 2020.
Chan JF, To KK, Tse H, Jin DY, Yuen KY. Interspecies transmission and emergence of novel viruses: Lessons from bats and birds. Trends Microbiol. 2013;21(10):544-55.
Sahin AR, Aysegul A, Agaoglu PM, Dineri Y, Cakirci AY, Senel ME, Okyay RA, Tasdogan AM. 2019 novel coronavirus (COVID-19) outbreak: A review of the current literature. 2020;4(1):1–7.
DOI: 10.14744/ejmo.2020.12220 EJMO
Chen TM, Rui J, Wang QP, Zhao ZY, Cui JA, Yin L. A mathematical model for simulating the transmission of Wuhan novel coronavirus. bioRxiv; 2020.
Wu P, Hao X, Lau EHY, Wong JY, Leung KSM, Wu JT, Cowling BJ, Leung GM. Real-time tentative assessment of the epidemiological characteristics of novel coronavirus infections in Wuhan, China, as at 22 January 2020. Euro Surveill. 2020;25.
World Health Organization, 2019- nCoV Situation Report-70 on 30 March; 2020.
Gralinski L, Menachery V. Return of the coronavirus: 2019-nCoV. Viruses. 2020;12: 135.
Chen Z, Zhang W, Lu Y, et al. From SARS-CoV to Wuhan 2019-nCoV outbreak: Similarity of early epidemic and prediction of future trends. Cell Press; 2020.
Corman VM, Landt O, Kaiser M, Molenkamp R, Mei-jer A, Chu DK, Bleicker T, Brünink S, Schneider J, Schmidt ML, Mulders DG, Haagmans BL, van der Veer B, van den Brink S, Wijsman L, Goderski G, Romette JL, Ellis J, Zambon M, Peiris M, Goossens H, Reusken C, Koopmans MP, Drosten C. Detection of 2019 novel coronavirus (2019-nCoV) by real-time RT-PCR. Euro Surveill. 2020;25.
Clinical management of severe acute respiratory infection when novel coronavirus (nCoV) infection is suspected [Internet].
[Cited 2020 Feb 11]
Hou C, Zhou JCY, Hua L, Yuan J, He S, Guo Y, Zhang S, Jia Q, Zhao C, Zhang J, Xu G, Jia E. The effectiveness of the quarantine of Wuhan city against the corona virus disease 2019 (COVID-19): Well-mixed SEIR model analysis; 2020.
Qing-Xia Ma, Hu Shan, Hong-Liang Zhang, Gui-Mei Li, Rui-Mei Yang, Ji-Ming Chen. Potential utilities of mask wearing and instant hand hygiene for fighting SARS COV-2; 2020.
Wu J, Li W, Shi X, Chen Z, Jiang B, Liu J. Early antiviral treatment contributes to alleviate the severity and improve the prognosis of patients with novel coronavirus disease (COVID‐19); 2020.
Hoek LVD, Pyrc K, Jebbink MF, Vermeulen-Oost W, Berkhout RJM, Wolthers KC, Wertheim-van Dillen PME, Kaandorp J, Spaargaren J, Berkhout B. Identification of a new human coronavirus. Article in Nature Medicine; 2004. Source: PubMed.
Tang N, Bai H, Chen X, Gong J, Li D, Sun Z. Anticoagulant treatment is associated with decreased mortality in severe coronavirus disease 2019 patients with coagulopathy; 2020.
Weiss SR, Navas-Martin S. Corona virus pathogenesis and the emerging pathogen severe acute respiratory syndrome corona virus. Microbiology and Molecular Biology Reviews. 2005;635–664.
Tian S, Hu W, Niu L, Liu H, Xu H, Xiao SY. Pulmonary pathology of early-phase 2019 novel coronavirus (COVID-19) pneumonia in two patients with lung cancer. Journal of Thoracic Oncology; 2020.
Casadevall A, Pirofski L. The convalescent sera option for containing COVID-19. J. Clin Invest. 2020;130(4):1545- 1548.
Cyranoski D. This scientist hopes to test coronavirus drugs on animals in locked-down Wuhan. Nature. 2020;577:607.
Schwartz RA, Janniger CK. Generalized pustular figurate erythema a newly delineated severe cutaneous drug reaction linked with hydroxychloroquine; 2020.
Gupta M, Abdelmaksoud A, Jafferany M, Sadoughifar TLR, Goldust M. COVID-19 and economy; 2020.
Data of Uttar Pradesh Pollution Board Collected from Daily News Paper Amar Ujala.
Most read articles by the same author(s)
- SHYAM GUPTA, STUDY OF ALP TOXICITY ON LARVAL STAGES OF Ephestia calidella (GUEN.) A PEST OF STORED DRY FRUITS , UTTAR PRADESH JOURNAL OF ZOOLOGY: 2019 - Volume 40 [Issue 1]