HISTOPATHOLOGY OF FENVALERATE ON TISSUES (HEPATIC, RENAL, & SKELETAL MUSCLE) OF Channa punctata

Main Article Content

PRIYA SINGH
RAKESH KUMAR PANDEY
DHANANJAY YADAV
ALIYA AIJAZ

Abstract

Fenvalerate is a pyrethroid insecticide that is employed in agriculture to combat a variety of pests. The goal of this study was to see how fenvalerate affected various organs of Channa punctata. Light microscopy was used to examine the histology of fenvalerate, a synthetic insecticide, onto the kidney, liver, muscle cells, and skeletal muscle tissues of Channa punctata, an Indian large carp species. For 10 days, the fish were subjected to sub-lethal quantities of fenvalerate,(0.6 ppb and 0.3 ppb). The tissues in the control group were normal. Vacuolization (V) was Observed in most tubules, renal tubule damage (DRT), Glomerular atrophy (GA), Increased Bowman's space (IBS), necrosis (N), and Pycknotic Nuclei (PN), these degenerative variations were seen in the kidney of pesticide-treated fish. Several alterations were found in the skeletal muscle of fish treated with pesticides. The pathological outcomes include vacuolar degeneration in muscle fiber, splitting in muscle fiber, degeneration in muscle fiber were seen.

The current study demonstrates its toxicity concerning the organ damage caused by fenvalerate. Fenvalerate concentrations in natural conditions were lower than those employed in this investigation, but continued use of the pesticide may lead to the concentrations used in the experiment.

Keywords:
Bowman's space, necrosis, pycknotic nuclei, degenerative variations, kidney of pesticide-treated fish

Article Details

How to Cite
SINGH, P., PANDEY, R. K., YADAV, D., & AIJAZ, A. (2021). HISTOPATHOLOGY OF FENVALERATE ON TISSUES (HEPATIC, RENAL, & SKELETAL MUSCLE) OF Channa punctata. UTTAR PRADESH JOURNAL OF ZOOLOGY, 42(23), 107-114. Retrieved from http://mbimph.com/index.php/UPJOZ/article/view/2617
Section
Original Research Article

References

Mahmoud AH, Darwish NM, Kim YO, Viayaraghavan P, Kwon JT, Na S, et al. Fenvalerate induced toxicity in Zebra fish, Danio rerio and analysis of biochemical changes and insights of digestive enzymes as important markers in risk assessment. Journal of King Saud University-Science. 2020;32(2): 1569–1580.

Turinek M, Grobelnik-Mlakar S, Bavec M, Bavec F. Biodynamic agriculture research progress and priorities. Renewable Agriculture and Food Systems. 2009;24(2):146–154.

Al-Sharbati MM, El-Burghthy S, Sudani OH. Accidental poisoning in children. Saudi Medical Journal. 1998;19(4):423–428.

Gupta Sanjay Kumar, Pal AK, Sahu NP, Saharan N, Mandal SC, Prakash C, Akhtar MS, Prusty AK. Dietary microbial levan ameliorates stress and augments immunity in C yprinus carpio fry (L innaeus, 1758) exposed to sublethal toxicity of fipronil. Aquaculture Research. 2014;45(5):893–906.

Ngidlo RT. Impacts of pesticides and fertilizers on soil, tail water and groundwater in three vegetable producing areas in the Cordillera Region, Northern Philippines. Journal of Experimental Agriculture International. 2013;780–793.

Gupta SK, Pal AK, Sahu NP, Jha AK, Akhtar MS, Mandal SC, Das P, Prusty AK. Supplementation of microbial levan in the diet of Cyprinus carpio fry (Linnaeus, 1758) exposed to sublethal toxicity of fipronil: effect on growth and metabolic responses. Fish Physiology and Biochemistry. 2013;39(6): 1513–1524.

Bussy U, Li K, Li W. Application of liquid chromatography-tandem mass spectrometry in quantitative bioanalyses of organic molecules in aquatic environment and organisms. Environmental Science and Pollution Research. 2016;23(10):9459–9479.

Relyea RA. The impact of insecticides and herbicides on the biodiversity and productivity of aquatic communities. Ecological Applications. 2005;15(2):618–627.

He F, Wang S, Liu L, Chen S, Zhang Z, Sun J. Clinical manifestations and diagnosis of acute pyrethroid poisoning. Archives of Toxicology. 1989;63(1):54–58.

Chen SY, Zhang ZW, He FS, Yao PP, Wu YQ, Sun JX, Liu LH, Li QG. An epidemiological study on occupational acute pyrethroid poisoning in cotton farmers. Occupational and Environmental Medicine. 1991;48(2):77–81.

Hadnagy W, Leng G, Sugiri D, Ranft U, Idel H. Pyrethroids used indoors–Immune status of humans exposed to pyrethroids following a pest control operation–a one year follow-up study. International Journal of Hygiene and Environmental Health. 2003;206(2):93– 102.

Soderlund DM, Clark JM, Sheets LP, Mullin LS, Piccirillo VJ, Sargent D, Stevens JT, Weiner ML. Mechanisms of pyrethroid neurotoxicity: Implications for cumulative risk assessment. Toxicology. 2002;171(1):3–59.

de Aguiar LH, Moraes G, Avilez IM, Altran AE, Corrêa CF. Metabolical effects of Folidol 600 on the neotropical freshwater fish matrinxã, Brycon cephalus. Environmental Research. 2004;95(2):224–230.

Sathyamoorthi A, Bhatt P, Ravichandran G, Kumaresan V, Arasu MV, Al-Dhabi NA, Arockiaraj J. Gene expression and in silico analysis of snakehead murrel interleukin 8 and antimicrobial activity of C-terminal derived peptide WS12. Veterinary Immunology and Immunopathology. 2017;190:1–9.

Sharma DK, Ansari BA. Effect of deltamethrin and a neem based pesticide achook on some biochemical parameters in tissues liver, ovary and muscle of zebra fish daniorerio (Cyprinidae). Res. J. Chem. Sci. 2011;1(4):125–134.

Adhikari S, Sarkar B, Chattopadhyay A, Chattopadhyay DN, Sarkar SK, Ayyappan S. Effect of cypermethrin on breeding performances of a freshwater fish, Labeo rohita (Hamilton). Chemistry and Ecology. 2006;22(3):211–218.

Coats JR, Symonik DM, Bradbury SP, Dyer SD, Timson LK, Atchison GJ. Toxicology of synthetic pyrethroids in aquatic organisms: an overview. Environmental Toxicology and Chemistry: An International Journal. 1989;8(8):671–679.

Cengiz EI. Gill and kidney histopathology in the freshwater fish Cyprinus carpio after acute exposure to deltamethrin. Environmental Toxicology and Pharmacology. 2006;22(2):200–204.

Cengiz EI, Unlu E. Sublethal effects of commercial deltamethrin on the structure of the gill, liver and gut tissues of mosquitofish, Gambusia affinis: a microscopic study. Environmental Toxicology and Pharmacology. 2006;21(3):246–253.

Chandra S, Ram RN, Singh IJ. Toxic effect of carbofuran on certain hematological parameters in yearlings of Cyprinus carpio. Aquacult. 2001;2(2):137–140.

Palanichamy S, Baskaran P, Balasubramanian MP. Sublethal effects of selected pesticides on protein, carbohydrate and lipid content of different tissues of Oreochromis mossambicus. Pesticide Residues and Environmental Pollution/SC Goel, Editor; 1986.

Barbee GC, McClain WR, Lanka SK, Stout MJ. Acute toxicity of chlorantraniliprole to non‐target crayfish (Procambarus clarkii) associated with rice–crayfish cropping systems. Pest Management Science. 2010;66(9):996–1001.

Gijare S, Raja IA, Tantarpale VT, Kulkarni KM. Influence of cypermethrin on liver of the freshwater fish Ophiocephalus punctatus. Pollution Research. 2011;31(1).

Grant BF, Mehrle PM. Chronic endrin poisoning in goldfish, Carassius auratus. Journal of the Fisheries Board of Canada. 1970;27(12):2225–2232.

Slaninova A, Smutna M, Modra H, Svobodova Z. Reviews Oxidative stress in fish induced by pesticides. Neuroendocrinology Letters. 2009;30(1):2.

Association APH, Association AWW, Federation WPC, Federation WE. Standard methods for the examination of water and wastewater (Vol. 2). American Public Health Association; 1912.

Çelik A, Mazmanci B, Çamlica Y, Çömelekoğlu Ü, Aşkin A. Evaluation of cytogenetic effects of lambda-cyhalothrin on Wistar rat bone marrow by gavage administration. Ecotoxicology and Environmental Safety. 2005;61(1):128–133.

Singh RN. Histopathological alterations in the kidney of Cyprinus carpio after exposure to dimethoate (EC 30%). Indian Journal of Scientific Research. 2012;3(1):127–131.

Gupta S, Dalela RC. Kidney damage in Notopterus notopterus(Pallas) following exposure to phenolic compounds. Journal of Environmental Biology. 1987;8(2):167– 172.

Csepai F. Szovettani vizsgalattal kimutathato dystrophiak nehany peszticid kronikus hatasanak kitett ponty vesejeben. Magyar Allatorvosok Lapja; 1978.

Sulodia S, Singh S, Sharma HN. (n.d.). Histopathological changes in Kidney of Channa punctatus (Bloch) under stress of Folidol. Journal of Advanced Laboratory Research in Biology. 5(3)86–90.

Das BK, Mukherjee SC. A histopathological study of carp (Labeo rohita) exposed to hexachlorocyclohexane. Veterinarski Arhiv. 2000;70(4):169–180.

Dutta HM, Adhikari S, Singh NK, Roy PK, Munshi JSD. Histopathological changes induced by malathion in the liver of a freshwater catfish, Heteropneustes fossilis (Bloch). Bulletin of Environmental Contamination and Toxicology. 1993; 51(6):895–900.

Velmurugan B, Selvanayagam M, Cengiz EI, Unlu E. Histopathology of lambda-cyhalothrin on tissues (gill, kidney, liver and intestine) of Cirrhinus mrigala. Environmental Toxicology and Pharmacology. 2007;24(3):286–291.

Fanta E, Rios FS, Romão S, Vianna ACC, Freiberger S. Histopathology of the fish Corydoras paleatus contaminated with sublethal levels of organophosphorus in water and food. Ecotoxicology and Environmental Safety. 2003;54(2):119–130.