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Chicken pox is a seasonal, highly contagious disease caused by varicella virus. This virus belongs to the herpesviridae family. Although its symptoms are mild, the attention is meager to prevent its dispersal. Varicella virus proportion is high in developing countries because of the rapid spread between students as a result of indirect contact with instruments and secretions of a patient, droplets and airborne diffusion of vesicular fluid.
Aim: This study aimed to find out the prevalence of Varicella in Nineveh province sectors from 2005-2018. Our statistical analysis was brought out from all sections of the province.
Results: In the last decade, the number of cases has been increased in Iraq due to lack of health awareness in addition to the lack of vaccine. To reduce number of infections, it is necessary to follow up the patients and detect the virus mutations.
Conclusion: Isolation of patients may decrease virus spreading. Moreover, using of the novel methods for diagnosis are more significant as well as assign of the clinical features.
CDC. Prevention of herpes zoster: recommendations of the advisory committee on immunization practices (ACIP) recom-mendations for use of herpes zoster vaccines. MMWR Recomm Rep. 2018;67(03):103-108.
Gershon AA, Breuer J, Cohen JI, Cohrs RJ, Gershon MD, Gilden D, Grose C, Hambleton S, Kennedy PGE, Oxman MN, Seward JF, Yamanishi K, Varicella zoster virus infection. Nat. Rev. Dis. Primers. 2015;1:15016.
Yih W, Brooks D, Lett S, Jumaan A, Zhang Z, Clements K, Seward J. The incidence of varicella and herpes zoster in Massachusetts as measured by the Behavioral Risk Factor Surveillance System (BRFSS) during a period of increasing varicella vaccine cover age external icon. BMC Public Health. 2005;5(68).
Hew K, Dahlroth SL, Veerappan S, Pan LX, Cornvik T, Nordlund P. Structure of the varicella zoster virus thymidylate synthase establishes functional and structural similarities as the human enzyme and potentiates itself as a target of brivudine. PLOS One. 2015;2.
John W, Gnann Jr. Human herpesviruses: Biology, therapy, and immunoprophylaxis. Cambridge University Press. 2007;65.
Russell ML, Dover DC, Simmonds KA, Svenson LW. Shingles in alberta: Before and after publicly funded varicella vaccination external icon. Vaccine.
Kruger DH, Mertens T. Classic paper: Are the chickenpox virus and the zoster virus identical? Rev Med Virol. 2018;28(3):e1975. DOI: 10.1002/rmv. 19 75.
Macartney K, Heywood A, McIntyre P. Vaccines for post-exposure prophylaxis against varicella (chickenpox) in children and adults. Cochrane Database Syst. Rev. 2014;(6): CD001833.
Weinmann S, Chun C, Schmid DS, Roberts M, Vandermeer M, Riedlinger K, et al. Incidence and clinical characteristics of herpes zoster among children in the varicella vaccine era, 2005–2009 external icon. J. Infe. Dis. 2013; 208(11):1859-68.
Hardy I, Gershon AA, Steinberg SP, LaRussa P. The incidence of zoster after immunization with live attenuated varicella vaccine. A study in children with leukemia. Varicella Vaccine Collaborative Study Groupexternal icon. N Engl J Med. 1991;325(22):1545-50.
Marin M, Chaves SS, Schmid S, Seward JF. Prevention of varicella. Recommendations of the Advisory Committee on Immunization Practices (ACIP). CDC. 2007;56(RR04):1-40.
Thomas SL, Hall AJ. What does epidemiology tell us about risk factors for herpes zoster? Lancet Infect Dis. 2004;4(1):26-33.
Vleck SE, Oliver SL, Brady JJ, Blau HM, Rajamani JR, Sommer MH, Arvin AM. Structure–function analysis of varicella-zoster virus glycoprotein H identifies domain-specific roles for fusion and skin tropism. PNAS. 2011; 108(45):18412–18417.
World Health Organization. Varicella and herpes zoster vaccines: WHO position paper, June 2014. Wkly Epidemiol Rec. 2014;89: 265–287.
Hales CM, Harpaz R, Joesoef MR, Bialek SR. Examination of links between herpes zoster incidence and childhood varicella vaccination external icon. Ann. Inte. Mede. 2013;159(11): 739-45.
Marin M, Güris D, Chaves SS, Schmid S, Seward JF. Prevention of varicella: Recom-mendations of the Advisory Committee on Immunization Practices (ACIP). MMWR Recomm Rep. 2007;56:1–40.
Lolekha S, et al. Effect of climatic factors and population density on varicella zoster virus epidemiology within a tropical country. Am J Trop Med Hyg. 2001;64:131–136.
Siedler A, Arndt U. Impact of the routine varicella vaccination program on varicella epidemiology in Germany. Euro Surveillance. 2010;15(13).
Bialek SR, et al. Impact of a routine two-dose varicella vaccination program on varicella epidemiology. Pediatrics. 2013;132:e1134–e1140.
Flatt A, Breuer J. Varicella vaccines. British Medical Bulletin. 2012;103(1):115–27.
WHO. Weekly epidemiological record. Varicella and herpes zoster vaccines: WHO Position Paper. 2004;89:265–288.
Wagstaff AJ, Bryson HM. Foscarnet: A reappraisal of its antiviral activity, pharma-cokinetic properties and therapeutic use in immuno compromised patients with viral infections. Drugs. 1994;48:199–226.
Ku CC, et al. Varicella-zoster virus transfer to skin by T cells and modulation of viral replication by epidermal cell interferon-α. J Exp Med. 2004;200:917–925.