THE NEUROPROTECTIVE EFFECTS OF MEDICINAL PLANTS ON ALZHEIMER`S DISEASE: A REVIEW

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Published: 2022-03-21

Page: 135-146


S. PRAJWAL

Department of Pharmacology, Sri Adichunchanagiri College of Pharmacy, Adichunchanagiri University, BG Nagara, Mandya, India.

M. RUPESH KUMAR *

Department of Pharmacology, Sri Adichunchanagiri College of Pharmacy, Adichunchanagiri University, BG Nagara, Mandya, India.

*Author to whom correspondence should be addressed.


Abstract

In the 21st century, the human population is suffering from a neurodegenerative disorder in which neuronal death occurs due to a long-term chronic condition causing substantial major health concerns. When neurons die, they are not regenerated, causing cognitive impairment, i.e., Alzheimer’s disease, Parkinson’s disease, schizophrenia, and dementia. This review concentrates only on Alzheimer’s disease aetiology and various plants having potent neuroprotective activity related to Alzheimer’s disease. The most common aetiology of Alzheimer’s disease is a deposition of APP protein, hyperphosphorylation of Tau protein, a reduction in acetylcholine and oxidative stress, which are discussed briefly. Moreover, pertinent evidence is also discussed for medicinal plants with potent or promising neuroprotective activity related to Alzheimer’s disease.

Keywords: Alzheimer’s disease, Bacopa monnieri, neuroprotective, pathophysiology, withania somnifera


How to Cite

PRAJWAL, S., & KUMAR, M. R. (2022). THE NEUROPROTECTIVE EFFECTS OF MEDICINAL PLANTS ON ALZHEIMER`S DISEASE: A REVIEW. Asian Journal of Advances in Medical Science, 4(1), 135–146. Retrieved from https://mbimph.com/index.php/AJOAIMS/article/view/2943

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