Emulgel of Rumex hastatus D. Don Methanolic Root Extract with Antifungal Activity: Formulation and Evaluation

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Published: 2023-12-28

Page: 94-102


Manju Koli *

Invertis Institute of Pharmacy, Invertis University Bareilly, U.P., India.

Kavita Lovanshi

SAM Global University, Gram Adampur Chawni Kolua, Raisen Road Bhopal, MP., India.

Vishesh Kumar Maurya

Rakshpal Bahadur, College of Pharmacy Bareilly, India.

Princee Verma

Rakshpal Bahadur, College of Pharmacy Bareilly, India.

Mohammad Rizwan

Department of Pharmaceutical Sciences, Sir J.C. Bose Technical Department, Kumaun University, Bhimtal, Nanital, Uttarakhand, 263136, India.

Vikas Saxena

Rakshpal Bahadur, College of Pharmacy Bareilly, India.

*Author to whom correspondence should be addressed.


Abstract

This study emphasised on the production of ‘Rumex Hastatus’ D. Don methanolic root extract for antifungal purposes. We performed a variety of physical and chemical analyses. We also executed many phytochemical investigations. Extracts from sequential hot percolation (Soxhlet) were subjected to preliminary phytochemical screening. The objective of this investigation was to formulate and analyze a herbal emulgel with antifungal activity based on Rumex hastatus root extract. "The purpose of this study is to determine the antifungal activity of herbal emulgel formulation using Rumex hastatus root extract" might serve as an appropriate substitute for the original sentence. The extract has antifungal properties and is used in the formulation as an active therapeutic product. The extraction employed methanol, and the yield was found to be 26%. many phytoconstituents were found in the extract, including alkaloids, flavonoids, saponins, tannins, phenols, and anthraquinone glycoside. Despite the fact that this is an early examination, the results show that the generated emulgel is effective, and the pure chemical responsible for the effect should be extracted and studied. All of the developed formulations were effective, although formulation F3 showed the most promising outcomes of the four compositions and can be recommended for pilot scale up after constituent isolation.

Keywords: Rumex, emulgel, hypodermis, anthraquinone, phytoconstituents


How to Cite

Koli , M., Lovanshi , K., Maurya , V. K., Verma, P., Rizwan , M., & Saxena , V. (2023). Emulgel of Rumex hastatus D. Don Methanolic Root Extract with Antifungal Activity: Formulation and Evaluation. Asian Journal of Advances in Medical Science, 5(1), 94–102. Retrieved from https://mbimph.com/index.php/AJOAIMS/article/view/3832

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