A Revised Novel Approach of Ischemic Stroke through Thrombolytic Therapy and Thrombectomy

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Published: 2024-01-02

Page: 1-11

Akula Ruchitha Sai

Department of Pharmacology, Raghavendra Institute of Pharmaceutical Education and Research, (RIPER) – Autonomous, KR Palli Cross, Chiyyedu (Post), Anantapur, Andhra Pradesh- 515721, India.

Aaravula Hemanth Babu

Department of Pharmacology, Raghavendra Institute of Pharmaceutical Education and Research, (RIPER) – Autonomous, KR Palli Cross, Chiyyedu (Post), Anantapur, Andhra Pradesh- 515721, India.

Mopuri jyothsna

Department of Pharmacology, Raghavendra Institute of Pharmaceutical Education and Research, (RIPER) – Autonomous, KR Palli Cross, Chiyyedu (Post), Anantapur, Andhra Pradesh- 515721, India.

K. Somasekhar Reddy

Department of Pharmacology, Raghavendra Institute of Pharmaceutical Education and Research, (RIPER) – Autonomous, KR Palli Cross, Chiyyedu (Post), Anantapur, Andhra Pradesh- 515721, India.

A. Sudheer *

Department of Pharmacology, Raghavendra Institute of Pharmaceutical Education and Research, (RIPER) – Autonomous, KR Palli Cross, Chiyyedu (Post), Anantapur, Andhra Pradesh- 515721, India.

*Author to whom correspondence should be addressed.


This comprehensive overview analyses the development of ischemic stroke therapy, emphasizing the critical significance that thrombolytic therapy and thrombectomy techniques have played. With a particular set of difficulties, thrombolytic therapy tissue plasminogen activator, or tPA has revolutionized acute stroke care by breaking up clots in a crucial window of time. Simultaneously, thrombectomy has become a revolutionary intervention, especially for large-vessel occlusions, offering a localized, effective approach and expanding therapy windows. This review guides you through the historical events, technological developments, and continuing research that have shaped these methods. The importance of individualized treatment plans, the use of telemedicine, and the bright future prospects for the management of ischemic strokes are emphasized.

Keywords: Thrombectomy, thrombolytic therapy, ischemic cascade, aspiration catheters, stent retrieval, combined therapy

How to Cite

Sai , A. R., Babu , A. H., jyothsna, M., Reddy, K. S., & Sudheer, A. (2024). A Revised Novel Approach of Ischemic Stroke through Thrombolytic Therapy and Thrombectomy. Asian Journal of Advances in Medical Science, 6(1), 1–11. Retrieved from https://mbimph.com/index.php/AJOAIMS/article/view/3834


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