EVALUATING THE ANTIBACTERIAL ACTIVITY OF MORINDA MORINDOIDES EXTRACTS ON THE IN VITRO GROWTH OF THE CLINICAL STRAINS OF Shigella sp.

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Published: 2021-07-12

Page: 639-649


KOFFI ALLALI EUGÈNE *

College of Agroforestry, Agrovalorisation Laboratory, Department of Biochemistry and Microbiology, Jean Lorougnon GUEDE University, P.O Box 150 Daloa, Côte d'Ivoire.

DOSSO MAMADOU

Biological Sciences, College of Biochemistry and Genetics, Peleforo Gon Coulibaly University, P.O Box 1328 Korhogo, Côte d'Ivoire.

ABBA P. OBOUAYEBA

College of Agroforestry, Agrovalorisation Laboratory, Department of Biochemistry and Microbiology, Jean Lorougnon GUEDE University, P.O Box 150 Daloa, Côte d'Ivoire.

DJAKO S. T. AKRÉ

College of Agroforestry, Agrovalorisation Laboratory, Department of Biochemistry and Microbiology, Jean Lorougnon GUEDE University, P.O Box 150 Daloa, Côte d'Ivoire.

N’GUESSAN KOUADIO MICHAEL

College of Agroforestry, Agrovalorisation Laboratory, Department of Biochemistry and Microbiology, Jean Lorougnon GUEDE University, P.O Box 150 Daloa, Côte d'Ivoire.

A. SAKIRIGUI

Laboratory of Pharmacognosy and Essential Oils, Faculty of Sciences and Techniques/University of Abomey-Calavi (UAC) Cotonou, Republic of Benin and Aromatic, Food and Medicinal Plants Research Laboratory, Faculty of Sciences and Techniques, UNSTIM/Abomey Republic of Benin, République du Bénin.

EHOUMAN MOCKET ADOLPHE

Olopam Pharma and Research & Development, Côte d'Ivoire.

A. B. ACKAH JACQUES AUGUSTE

College of Agroforestry, Agrovalorisation Laboratory, Department of Biochemistry and Microbiology, Jean Lorougnon GUEDE University, P.O Box 150 Daloa, Côte d'Ivoire.

*Author to whom correspondence should be addressed.


Abstract

For a couple of years, strains of Shigella resistant to aminopenicillins and cotrimoxazole have developed and have become predominant.

 The purpose of paper is to show the social contribution in the care of gastroenteritis. As such,  the antibacterial activity of the total aqueous and 70% ethanolic extracts of the leaves of Morinda morindoides, a plant from the Ivorian pharmacopoeia was evaluated.

In this paper, bacteriological tests were carried out on two pathogenic strains of Shigella sp. (EEQ and 1055).

The methods of diffusion, either  in agar medium or in liquid, were used for the search for Minimal Inhibitory Concentration (MIC) and Minimal Bactericidal Concentration (MBC).

The results show that both extracts tested have in vitro antibacterial bactericidal efficiency on both Shigella sp. strains. However, the 70% ethanolic extract which is twice as effective as the total aqueous extract is more active against strains of Shigella Sp  tested, with a MBC of 25 mg/mL.

The finding suggest that antibacterial properties of this plant could also useful for caring shigellosis.

Keywords: Morinda morindoides, aqueous extract, ethanolic extract, bacterial strains, Shigella sp., MBC, MIC


How to Cite

EUGÈNE, K. A., MAMADOU, D., OBOUAYEBA, A. P., AKRÉ, D. S. T., MICHAEL, N. K., SAKIRIGUI, A., ADOLPHE, E. M., & AUGUSTE, A. B. A. J. (2021). EVALUATING THE ANTIBACTERIAL ACTIVITY OF MORINDA MORINDOIDES EXTRACTS ON THE IN VITRO GROWTH OF THE CLINICAL STRAINS OF Shigella sp. Asian Journal of Advances in Research, 4(1), 639–649. Retrieved from https://mbimph.com/index.php/AJOAIR/article/view/2277

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