A Systematic Review of Natural Products for the Alzheimer's Disease

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Published: 2024-04-18

Page: 141-150


Mopuri Jyothsna

Department of Pharmacology, Raghavendra Institute of Pharmaceutical Education and Research (RIPER) – Autonomous, KR Palli Cross, Chiyyedu (Post), Anantapur, Andhra Pradesh, 515721, India.

Akula Ruchitha Sai

Department of Pharmacology, Raghavendra Institute of Pharmaceutical Education and Research (RIPER) – Autonomous, KR Palli Cross, Chiyyedu (Post), Anantapur, Andhra Pradesh, 515721, India.

Aaravula Hemanth Babu

Department of Pharmacology, Raghavendra Institute of Pharmaceutical Education and Research (RIPER) – Autonomous, KR Palli Cross, Chiyyedu (Post), Anantapur, Andhra Pradesh, 515721, India.

Buddadasari Snehitha

Department of Pharmacology, Raghavendra Institute of Pharmaceutical Education and Research (RIPER) – Autonomous, KR Palli Cross, Chiyyedu (Post), Anantapur, Andhra Pradesh, 515721, India.

K Baktha Bandhavi

Department of Pharmacology, Raghavendra Institute of Pharmaceutical Education and Research (RIPER) – Autonomous, KR Palli Cross, Chiyyedu (Post), Anantapur, Andhra Pradesh, 515721, India.

K Somasekhar Reddy

Department of Pharmacology, Raghavendra Institute of Pharmaceutical Education and Research (RIPER) – Autonomous, KR Palli Cross, Chiyyedu (Post), Anantapur, Andhra Pradesh, 515721, India.

Bhupalam Pradeep Kumar *

Department of Pharmacology, Raghavendra Institute of Pharmaceutical Education and Research (RIPER) – Autonomous, KR Palli Cross, Chiyyedu (Post), Anantapur, Andhra Pradesh, 515721, India.

*Author to whom correspondence should be addressed.


Abstract

Alzheimer's disease (AD) is a progressive neurodegenerative disorder marked by the accumulation of tau tangles and amyloid plaques, which results in cognitive decline. Natural substances and phytomedicines with antioxidant, anti-inflammatory, anti-amyloidogenic, and neuroprotective properties offer promising therapeutic modalities for AD. The investigation of these plant-based remedies is in line with the goal of developing safe, effective, multimodal, and culturally sensitive therapies that can be used to manage or cure a variety of illnesses while minimizing side effects and enhancing general health. The antioxidant effectiveness of these treatments is demonstrated by a number of patents, with the inhibition of tau hyperphosphorylation among the suggested mechanisms. In addition, a few natural extracts show promise in crossing the blood-brain barrier, and some have anti-inflammatory qualities as well.

Keywords: Alzheimer's disease, cognitive impairment, health disorders, phytomedicines


How to Cite

Jyothsna , M., Sai , A. R., Babu, A. H., Snehitha, B., Bandhavi , K. B., Reddy , K. S., & Kumar , B. P. (2024). A Systematic Review of Natural Products for the Alzheimer’s Disease. Asian Journal of Advances in Research, 7(1), 141–150. Retrieved from https://mbimph.com/index.php/AJOAIR/article/view/4032

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