EFFECT OF METHANOLIC EXTRACTS OF Artemisia pallens ON DIABETIC RATS CONSIDERING HAEMATOLOGICAL AND BLOOD SUGAR PARAMETERS

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Published: 2021-11-01

Page: 52-56


K. SAI PAVITHRA *

P.G. and Research Department of Biotechnology, Thanthai Hans Roever College of Arts and Science, Affiliated to Bharathidasan University, Perambalur, India.

JEYANTHI ANNADURAI

P.G. and Research Department of Biotechnology, Thanthai Hans Roever College of Arts and Science, Affiliated to Bharathidasan University, Perambalur, India.

R. RAGUNATHAN

Centre for Bioscience and Nanoscience Research, Affiliated to Bharathiar University, Coimbatore, India.

*Author to whom correspondence should be addressed.


Abstract

Artemisia species are extensively used for the management of diabetes in folklore medicine especially in the Asian continent. This study was designed to induce diabetes and also to investigate the effect of methanolic extracts of A. pallens on male albino rats. Diabetes was induced by the intraperitoneal administration of streptozotocin with nicotinamide (60 mg/kg b.w.). Artemisia extracts maintained the blood cell count in the treated rat system than the treated diabetic rats. Similarly, the blood and urine sugar levels also significantly changed compared to the control. Significant changes in the blood of the Artemisia treated rats represented the enhanced bone marrow production which resulted in resolution in metabolism along with regulation of heamatocytes and blood sugar levels. In addition, the urine sugar level was also significantly reduced. The current study demonstrated revealed the improved haematopoietic mechanism and anti-diabetic effects of methanolic extracts of A. pallens on male albino rats.

Keywords: Artemisia pallens, haematology, rat blood, glycosylated haemoglobin, diabetes, plasma insulin, urine insulin


How to Cite

PAVITHRA, K. S., ANNADURAI, J., & RAGUNATHAN, R. (2021). EFFECT OF METHANOLIC EXTRACTS OF Artemisia pallens ON DIABETIC RATS CONSIDERING HAEMATOLOGICAL AND BLOOD SUGAR PARAMETERS. UTTAR PRADESH JOURNAL OF ZOOLOGY, 42(22), 52–56. Retrieved from https://mbimph.com/index.php/UPJOZ/article/view/2557

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