Effect of Ginger on Cardiac Oxidative Stress and Carbohydrate Metabolic Profiles in STZ Induced Diabetic Rats
C. Narasimha Rao
Department of Zoology, Government Degree College, Mydukur, Andhra Pradesh, India.
P. Giridhar
Department of Zoology, Government College (A), Anantapur, Andhra Pradesh, India.
B. Sreedevi
Department of Zoology, Government College (A), Anantapur, Andhra Pradesh, India.
R. Manohar Srinivas Naik
Department of Zoology, Yogi Vemana University, Kadapa, Andhra Pradesh, India.
G L N Prasad
Department of Zoology, Government College (A), Anantapur, Andhra Pradesh, India and Department of Zoology, Yogi Vemana University, Kadapa, Andhra Pradesh, India.
D. Veera Nagendra Kumar *
Department of Zoology, Government College for Men (A), Kadapa, Andhra Pradesh, India.
*Author to whom correspondence should be addressed.
Abstract
The purpose of this research was to investigate how ginger can protect oxidative stress (antioxidant status) and carbohydrate metabolism in rats with induced diabetes. In this study we observed in diabetic rats, activities of SOD, CAT, GSH content, total carbohydrates, and total proteins decreased, while glycogen content was increased. However, administering ginger to diabetic rats led to an improvement in antioxidant status, total carbohydrates, total proteins and a decrease in glycogen levels. These results indicate that ginger has antioxidant and other medicinal properties that can regulate carbohydrate metabolism in diabetic rats.
Keywords: Diabetes, ginger, SOD, GSH, glycogen