In-silico ANALYSIS OF PHYTOCHEMICALS FROM Linum usitatissimum AGAINST Staphylococcus aureus CAUSING ECZEMA
ATASI ROUTRAY
Centurion University of Technology and Management, Odisha, India.
PRAJNA PRIYADARSINI SETHI
Centurion University of Technology and Management, Odisha, India.
RUNKI PRIYADARSINI SAMAL
Centurion University of Technology and Management, Odisha, India.
MUKUNDJEE PANDEY
Centurion University of Technology and Management, Odisha, India and Go to Market Laboratory, Gram Tarang, Odisha, India.
DIPANKAR BHATTACHARYAY *
Centurion University of Technology and Management, Odisha, India and Go to Market Laboratory, Gram Tarang, Odisha, India.
*Author to whom correspondence should be addressed.
Abstract
Eczema is caused by “Staphylococcus aureus”. Aspatate semialdehyde “dehydrogenase” is one of its major enzyme. Linum usitatissimum is known to cure eczema. The plant extract contains different phytochemical compounds. By using “Biovia Discovery Studio”, “molecular docking” of the phytochemicals with the enzymes was studied. The results showed that Linum usitatissimum can deactivate the aspatate semialdehyde dehydrogenase enzyme in that way interrupting the microbe’s life cycle.
Keywords: Phytochemicals, Linum usitatissimum, Staphylococcus aureus.
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