PREVENTION OF Haemophilus influenza CAUSING BRONCHITIS BY Curcuma amada
ARYARATNA MANGALDEEP
Centurion University of Technology and Management, Odisha, India.
ANWESHA APARAMITA NAYAK
Centurion University of Technology and Management, Odisha, India.
BISWARANJAN SHAOO
Centurion University of Technology and Management, Odisha, India.
MUKUNDJEE PANDEY
Centurion University of Technology and Management, Odisha, India.
DIPANKAR BHATTACHARYAY *
Centurion University of Technology and Management, Odisha, India.
*Author to whom correspondence should be addressed.
Abstract
Bronchitis is caused by Haemophilus influenza. Shikimate dehydrogenase is one of its major enzyme. Curcuma amada plant is known to cure of bronchitis. The plant extract contains different phytochemical compounds. By using “Biovia Discovery Studio”, the molecular docking of the phytochemicals with the enzymes was studied. The results showed thatar-tumeronecan deactivate the Shikimate dehydrogenase enzyme thereby interrupting the Haemophiluslife cycle.
Keywords: Phytochemical, Curcuma amada, Haemophilus influenzae.