PHYTOMEDICINAL EFFECT OF Nardostachys jatamansi AGAINST DERMATITIS CAUSING Staphylococcus aureus: AN In silico ANALYSIS
SWETANGINEE GOUDA
Centurion University of Technology and Management, Odisha, India.
PRERANA JENA
Centurion University of Technology and Management, Odisha, India.
SUNANYA DAS
Centurion University of Technology and Management, Odisha, India.
MUKUNDJEE PANDEY *
Centurion University of Technology and Management, Odisha, India and Go to Market Laboratory, Gram Tarang, Odisha, India.
DIPANKAR BHATTACHARYAY
Centurion University of Technology and Management, Odisha, India.
*Author to whom correspondence should be addressed.
Abstract
Dermatitis is caused by Staphylococcus aureus. Alcohol dehydrogenase is one of its major enzymes. Nardostachys jatamansi is known to cure of dermatitis. The plant extract contains different phytochemical compounds. By using “Biovia Discovery Studio”, the molecular docking of the phytochemicals with the enzymes was studied. The results showed that phytochemicals1-octacosanol and beta-sitosterol can deactivate the alcohol dehydrogenase enzyme thereby interrupting the microbe’s life cycle.
Keywords: Phytochemical, Nardostachys jatamansi, Staphylococcus epidermidis.