PREVENTION OF Haemophilus influenza CAUSING BRONCHITIS BY Ocimum tenuiflorum
DEBASMITA DAS
Centurion University of Technology and Management, Odisha, India.
SUNANYA DAS
Centurion University of Technology and Management, Odisha, India.
MUKUNDJEE PANDEY *
Centurion University of Technology and Management, Odisha, India and Go to Market Laboratory, Gram Tarang, Odisha, India.
DIPANKAR BHATTACHARYAY
Centurion University of Technology and Management, Odisha, India and Go to Market Laboratory, Gram Tarang, Odisha, India.
*Author to whom correspondence should be addressed.
Abstract
Bronchitis is caused by Haemophilus influenza. Adenine specific DNA methyltransferase is one of its major enzymes. Ocimum tenuiflorum is known to cure of Bronchitis. The plant extract contains different phytochemical compounds. By using “Biovia Discovery Studio”, the molecular docking of the phytochemicals with the enzymes was studied. The results showed that Rosmarinic Acid can deactivate the Adenine specific DNA methyltransferase enzyme thereby interrupting the microbe’s life cycle.
Keywords: Phytochemical, Ocimum tenuiflorum, Haemophilus influenza.