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Arsenic contamination in natural water resources has become a great task throughout the world which poses serious health problems, being the toxic agent in the ecosystem. The fishes are exposed to it through their skin, gills and by the intake of arsenic contaminated food and water. In the present investigation histological examination of liver and kidney of Chhilpura pond water treated fishes (Clarias batrachus) has severe histopathological changes like lobules of hepatocyte cell, lytic hepatocytes, mild infiltration, haemorrhage, disruption of normal architecture and fatty degeneration steatosis. In kidney it causes, inflammation, haemorrhage and shrinkage of glomerulus, congestion of vessels and rapture of Bowman’s capsules, etc. The present investigation suggested that the arsenic contaminated water showing high toxicity level.
Pichhode M, Gaherwal S. Catfish, Clarias batrachus. Int. J. Cur. Res. Rev. 2019;11(16):10.
Pichhode M, Kumar N. Effect of copper mining dust on the soil and vegetation in India: A critical review. International Journal of Modern Sciences and Engineering Technology. 2015;2(2):73-6.
Katare J, Pichhode M, Kumar N. Effect of different mining dust on the vegetation of district balaghat, MP-A critical review. International Journal of Science and Research. 2015;4(8):603-7.
Pichhode M, Gaherwal S. Study of sodium arsenate induced haematological changes in catfish, Clarias batrachus. Int. J. Biol. Med. Res. 2019;10(4):6882-5.
Ng JC, Wang J, Shraim A. A global health problem caused by arsenic from natural sources. Chemosphere. 2003;52(9):1353- 1359.
Tišler T, Zagorc-Končan J. Acute and chronic toxicity of arsenic to some aquatic organisms. Bulletin of Environmental Contamination and Toxicology. 2002;69(3):421-429.
Das S, Unni B, Bhattacharjee M, Wann SB, Rao PG. Toxicological effects of arsenic exposure in a freshwater teleost fish, Channa punctatus. African Journal of Biotechnology. 2012;11(19):4447-4454.
Bears H, Richards JG, Schulte PM. Arsenic exposure alters hepatic arsenic species composition and stress-mediated gene expression in the common killi fish (Fundulus heteroclitus). Aquatic Toxicology. 2006;77(3): 257-266.
Pedlar RM, Ptashynski MD, Wautier KG, Evans RE, Baron CL, Klaverkamp JF. The accumulation, distribution and toxicological effects of dietary arsenic exposure in lake white fish (Coregonus clupeaformis) and lake trout (Salvelinus namaycush). Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology. 2002;131(1):73-91.
Pedlar RM, Ptashynski MD, Evans R, Klaverkamp JF. Toxicological effects of dietary arsenic exposure in Lake Whitefish (Coregonus clupeaformis). Aquatic Toxicology. 2002;57(3):167-189.
Datta S, Ghosh D, Saha DR, Bhattacharaya S, Mazumder S. Chronic exposure to low concentration of arsenic is immunotoxic to fish: role of head kidney macrophages as biomarkers of arsenic toxicity to Clarias batrachus. Aquatic Toxicology. 2009;92(2):86-94.
Kotsanis N, Iliopoulou‐Georgudaki J, Kapata‐Zoumbos K. Changes in selected haematological parameters at early stages of the rainbow trout, Oncorhynchus mykiss, subjected to metal toxicants: arsenic, cadmium and mercury. Journal of Applied Ichthyology. 2000;16(6):276-278.
Hughes CM. General anatomy of the gills. In: Hoar RDJ, Marshal WS, Editors. Fish Physiology, New York: Academic Press. 1984;1–72.
Vardhani VV, Gowri P. Antigen induced histological changes in liver and kidney of Labeo rohita. Journal of Ecotoxicology and Environmental Monitoring. 2002;12(3):209-214.
Chen JC, Lin CH. Toxicity of copper sulfate for survival, growth, molting and feeding of juveniles of the tiger shrimp, Penaeus monodon. Aquaculture. 2001;192(1):55-65.
Schwaiger J, Ferling H, Mallow U, Wintermayr H, Negele RD. Toxic effects of the non-steroidal anti-inflammatory drug diclofenac: Part I: Histological alterations and bioaccumulation in rainbow trout. Aquatic Toxicology. 2004;68(2):141-150.
Paul DK. Government of India, Geological Survey of India; 1971.
Pichhode M, Gaherwal S. Effect of heavy metal toxicity, arsenic trioxide on the biochemical parameter of fresh water fish, Clarias batrachus. Poll. Res. 2020;39(Suppl.): 123-125.
Lillie RD. Histological technique and practical histochemistry. The Blackistone Comp. Inc. New York. Toronto. 1954;1:501.
Roy S, Bhattacharya S. Arsenic induced histology and synthesis of stress protein in liver and kidney of Channa panctatus. Ecotoxicol. Environ. Saf. 2006;65(2):218-229.
Das BK, Mukherjee SC. A histological study of carp (Labeo rohita) exposed to hexachlorocyclohexane. Veterinarski Arhiv. 2000;70(4):169-180.
Mohssen M. Biochemical and histological changes in serum creatinine and kidney induced by inhalation of Thimet (Phorate) in male Swiss albino mouse, Mus musculus. Environmental Research. 2001;87(1):31-6.
Durmaz H, Sevgiler Y, Uner N. Tissue specific antioxidative and neurotoxic response to diazinon in Oreochromis niloticus. Pesticide Biochemistry and Physiology. 2006;84(3):215-226.
Bashir S, Sharma Y, Irshad M, Gupta SD, Dogra TD. Arsenic induced cell death in liver and brain of experimental rats. Basic and Clinical Pharmacology and Toxicology. 2006;98(1):38-43.
Santra A, Chowdhury A, Ghatak S, Biswas A, Dhali GK. Arsenic induces apoptosis in mouse liver is mitochondria dependent and is abrogated by N-acetylcysteine. Toxicology and Applied Pharmacology. 2007;220(2):146-155.
Allah NH, Hameid A. A protective effect of calcium carbonate against arsenic toxicity of the Nile catfish, Clarias gariepinus. Turkish Journal of Fisheries and Aquatic Sciences. 2009;9:191-200.
Devaraju T, Sujatha K, Rao SM, Rao KJ. Impact of sodium arsenate on selected enzymes and histological studies in albino mice. International Journal of Pharmacy and Biological Sciences. 2010;1(3):344-354.
Aliaa M, Issa Azza, Gawish M. Histological hazards of Chlorprifos usage on gills and kidney of Thilapia nilotica and role of vitamin E supplement in Egypt. Life Science Journal. 2011;8(4):113-123.
Pichhode M, Gaur P, Khan HR, Dudwe J, Gaherwal S. Histological alteration caused by arsenic trioxide in catfish, Clarias batrachus. Journal of Xidian University. 2020;14(3):124-137.