In silico ANALYSIS OF EFFECT OF PHYTOCHEMICALS FROM Pavonia odorata AGAINST Epidermophyton floccosum CAUSING ATHLETES FOOT DISEASE
SIDHARTHA RAY
Centurion University of Technology and Management, Odisha, India.
SURAJ KUMAR SAHU
Centurion University of Technology and Management, Odisha, India.
JOGESH KUMAR NAYAK
Centurion University of Technology and Management, Odisha, India.
NABAKRUSHNA BEHERA
Centurion University of Technology and Management, Odisha, India.
MUKUNDJEE PANDEY *
GAGAN KUMAR PANIGRAHI
Centurion University of Technology and Management, Odisha, India.
*Author to whom correspondence should be addressed.
Abstract
Epidermophyton floccosum causes athletes foot disease. Strikingly, athlete’s foot disease rises primarily during specific molecular events, thus acting as a potential clinical biomarker. Further, athlete’s foot disease may also activate further downstream events, supporting the detrimental phase. To restrict the activity of athletes foot disease, several bio molecules can be deployed, of which the phytochemicals can be the best alternative. Molecular docking-based screening of a few phytochemicals revealed that the phytochemicals effectively associate with the active site of the protein and hence bears diagnostic and therapeutic potentials against athletes’ foot disease.
Keywords: Phytochemical, biovia, discovery studio, atheletes foot disease, epidermophyton