HYPERBILIRUBINEMIA EVALUATION AS A NEW DIAGNOSTIC MARKER FOR ACUTE APPENDICITIS

Main Article Content

A. Y. KSHIRSAGAR
V. V. KANSE
UMESH CHOUGULE
SURESH KOLEKAR
B. S. JOSHI
A. G. DAS

Abstract

Acute appendicitis is very usual common surgery emergency and early surgical action increases result. Treatment of appendicitis may be difficult and it is necessary to provide a strong index of concern to avoid severe problems from this condition. In order to test its efficacy as a diagnostic marker for acute appendicitis, this study was performed to examine the association among hyperbilirubinemia and acute appendicitis. This was a retrospective, single-center cohort research performed by the Surgery Department at KMIS, Karad. Duration of the study was from November 2013 to June 2015. Serum bilirubin is a major complement to the treatment of gangrene / perforated appendicitis. Our results indicate there is a strong sensitivity in hyperbilirubinaemia to differentiate acute appendicitis.

Keywords:
Hyperbilirubinemia, appendix, acute appendicitis, serum bilirubin, evaluation, diagnosis.

Article Details

How to Cite
KSHIRSAGAR, A. Y., KANSE, V. V., CHOUGULE, U., KOLEKAR, S., JOSHI, B. S., & DAS, A. G. (2020). HYPERBILIRUBINEMIA EVALUATION AS A NEW DIAGNOSTIC MARKER FOR ACUTE APPENDICITIS. UTTAR PRADESH JOURNAL OF ZOOLOGY, 41(18), 35-38. Retrieved from https://mbimph.com/index.php/UPJOZ/article/view/1721
Section
Original Research Article

References

Minneci PC, Mahida JB, Lodwick DL, Sulkowski JP, Nacion KM, Cooper JN, Ambeba EJ, Moss RL, Deans KJ. Effectiveness of patient choice in nonoperative vs surgical management of pediatric uncomplicated acute appendicitis. JAMA surgery. 2016;151(5):408-15.

Ramaswami YB, Prakash HS, TC RP, Jabbar FA. Hyperbilirubinemia: a new diagnostic marker for appendicular perforation. International Surgery Journal. 2017;4(9):3024-7.

Sahm M, Pross M, Otto R, Koch A, Gastinger I, Lippert H. Clinical health service research on the surgical therapy of acute appendicitis. Annals of Surgery. 2015;262(2):338-46.

Sand M, Bechara F, Holland-Letz T, Sand D, Mehnert G, Mann B. Diagnostic value of hyperbilirubinemia as a predictive factor for appendiceal perforation in acute appendicitis. Am J Surg. 2009;198:193-198.

Patel D, Shah NJ, Patel B, Parikh M, Patel D, Dalal C. Evaluation of hyperbilirubinemia as a new diagnostic marker for acute appendicitis and its role in the prediction of complicated appendicitis. Int J Res Med. 2014;3(3):28-33.

Abdellaa MR, Sayedb N. Elevated serum bilirubin as a preoperative specific predictor for complicated appendicitis in children. The Egyptian Journal of Surgery. 2015;34:71–78.

Wani MD, Mir SA, Bhat JA, Gul S, Maqbool U, Moheen HA. Hyperbilirubinemia, C‑ reactive protein and ultrasonography as predictors of appendiceal perforation: A prospective study. Saudi Surg J. 2014;2:1-5.

Burcharth J, Pommergaard HC, Rosenberg J, Gögenur I. Hyperbilirubinemia as a Predictor for Appendiceal Perforation: A Systematic Review. Scandinavian Journal of Surgery. 2013;102:55–60.

Ambre SR, Chavan S. Hyperbilirubinemia as a diagnostic marker for acute appendicitis. International Surgery Journal. 2018;5(6):2091-6.

Khan S. The diagnostic value of hyperbilirubinemia and total leukocyte count in the evaluation of acute appendicitis. J ClinDiagn Res. 2009;3:1647-1652.

Acharya A, Markar SR, Ni M, Hanna GB. Biomarkers of acute appendicitis: systematic review and cost–benefit trade-off analysis. Surgical Endoscopy. 2017;31(3):1022-31.

Panagiotopoulou IG, Parashar D, Lin R, Antonowicz S, Wells AD, Bajwa FM, Krijgsman B. The diagnostic value of white cell count, C-reactive protein and bilirubin in acute appendicitis and its complications. The Annals of the Royal College of Surgeons of England. 2013;95(3):215-21.

Adams HL, Jaunoo SS. Hyperbilirubinaemia in appendicitis: the diagnostic value for prediction of appendicitis and appendiceal perforation. European Journal of Trauma and Emergency Surgery. 2016;42(2):249-52.

Boshnak N, Boshnaq M, Elgohary H. Evaluation of platelet indices and red cell distribution width as new biomarkers for the diagnosis of acute appendicitis. Journal of Investigative Surgery. 2018;31(2):121-9.