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Acute appendicitis is very usual common surgery emergency and early surgical action increases result. Treatment of appendicitis may be difficult and it is necessary to provide a strong index of concern to avoid severe problems from this condition. In order to test its efficacy as a diagnostic marker for acute appendicitis, this study was performed to examine the association among hyperbilirubinemia and acute appendicitis. This was a retrospective, single-center cohort research performed by the Surgery Department at KMIS, Karad. Duration of the study was from November 2013 to June 2015. Serum bilirubin is a major complement to the treatment of gangrene / perforated appendicitis. Our results indicate there is a strong sensitivity in hyperbilirubinaemia to differentiate acute appendicitis.
Ramaswami YB, Prakash HS, TC RP, Jabbar FA. Hyperbilirubinemia: a new diagnostic marker for appendicular perforation. International Surgery Journal. 2017;4(9):3024-7.
Sahm M, Pross M, Otto R, Koch A, Gastinger I, Lippert H. Clinical health service research on the surgical therapy of acute appendicitis. Annals of Surgery. 2015;262(2):338-46.
Sand M, Bechara F, Holland-Letz T, Sand D, Mehnert G, Mann B. Diagnostic value of hyperbilirubinemia as a predictive factor for appendiceal perforation in acute appendicitis. Am J Surg. 2009;198:193-198.
Patel D, Shah NJ, Patel B, Parikh M, Patel D, Dalal C. Evaluation of hyperbilirubinemia as a new diagnostic marker for acute appendicitis and its role in the prediction of complicated appendicitis. Int J Res Med. 2014;3(3):28-33.
Abdellaa MR, Sayedb N. Elevated serum bilirubin as a preoperative speciﬁc predictor for complicated appendicitis in children. The Egyptian Journal of Surgery. 2015;34:71–78.
Wani MD, Mir SA, Bhat JA, Gul S, Maqbool U, Moheen HA. Hyperbilirubinemia, C‑ reactive protein and ultrasonography as predictors of appendiceal perforation: A prospective study. Saudi Surg J. 2014;2:1-5.
Burcharth J, Pommergaard HC, Rosenberg J, Gögenur I. Hyperbilirubinemia as a Predictor for Appendiceal Perforation: A Systematic Review. Scandinavian Journal of Surgery. 2013;102:55–60.
Ambre SR, Chavan S. Hyperbilirubinemia as a diagnostic marker for acute appendicitis. International Surgery Journal. 2018;5(6):2091-6.
Khan S. The diagnostic value of hyperbilirubinemia and total leukocyte count in the evaluation of acute appendicitis. J ClinDiagn Res. 2009;3:1647-1652.
Acharya A, Markar SR, Ni M, Hanna GB. Biomarkers of acute appendicitis: systematic review and cost–benefit trade-off analysis. Surgical Endoscopy. 2017;31(3):1022-31.
Panagiotopoulou IG, Parashar D, Lin R, Antonowicz S, Wells AD, Bajwa FM, Krijgsman B. The diagnostic value of white cell count, C-reactive protein and bilirubin in acute appendicitis and its complications. The Annals of the Royal College of Surgeons of England. 2013;95(3):215-21.
Adams HL, Jaunoo SS. Hyperbilirubinaemia in appendicitis: the diagnostic value for prediction of appendicitis and appendiceal perforation. European Journal of Trauma and Emergency Surgery. 2016;42(2):249-52.
Boshnak N, Boshnaq M, Elgohary H. Evaluation of platelet indices and red cell distribution width as new biomarkers for the diagnosis of acute appendicitis. Journal of Investigative Surgery. 2018;31(2):121-9.