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Hepatitis B virus infection (HBV) is a global public health problem. Nearly two billion people in the world have been acutely infected by HBV and there are nearly 350 million people chronically infected with HBV. In this research study Population based hepatitis survey was carried out to estimate sero-prevalence of hepatitis B virus (HBV) infection for the Kachipura population which is located in Nagpur Dharampeth area (India). Random sampling of population has been done. Oral consent was taken before taking blood sample. The selected population could answer the questionnaire. All age group people are selected for sampling. Prevalence of hepatitis B surface antigen and its associated factors in Kachipura population has been studied. Also study the relation between hepatitis B positive and various symptomatic characteristics. Effect of various risk factor like drug abuse, food habits have been studied. Blood samples were taken and serological analysis of collected blood samples has been done using HBsAg kit. Data were analyzed using standard biostatistician tool and software SPSS. 1.86% of prevalence rate of hepatitis B viral infection has been found in the population of Kachipura. Relation between blood groups and HBsAg positive has been found that the people with ORh+ve blood group are very prone to Hepatitis B infection.
Satsangi S, Chawla YK. Viral hepatitis: Indian scenario. Medical Journal Armed Forces India. 2016;72(3):204-210.
Tanga AT. Sero-prevalence of hepatitis B virus and associated factors among pregnant women in Gambella hospital, south wstern Ethiopia: facility based cross-sectional study.BCM Infectious Disease. 2019;1-7.
Goldstein ST, Zhou F, Hadler SC, Bell BP, Mast EE, Margolis HS. A mathematical model to estimate global hepatitis B disease burden and vaccination impact. International Journal of Epidemiology. 2005;34(6):1329-1339.
Veselíny E, Janičko M, Dražilová S, Siegfried L, Pastvová L, Schréter I,Cáriková K. High hepatitis B and low hepatitis C prevalence in Roma population in eastern Slovakia. Central European Journal of Public Health. 2014;22(Supplement):S51-S56.
Lok AS, McMahon BJ. Chronic hepatitis B: update, 2009.
Kluwer W.Elimination of viral hepatitis in India.Indian Journal of Public Health. 2019;275-276.
Obi RK. Nutritional interventions in reducing morbidity and mortality in people with human immunodeficiency virus. In Health of HIV Infected People. Academic Press. 2015;483-507.
Kumar A. Hepatitis B virus genotype A is more often associated with severe liver disease in northern India than is genotype D," Indian Journal Gastroenterol. 2005;19-22.
Gupta S, Gupta R, Joshi YK, Singh S. Role of horizontal transmission in hepatitis B virus spread among household contacts in north India. Intervirology. 2008;51(1):7-13.
Dwivedi M. Seroprevalence of hepatitis B infection during preganacy and risk of perinatal transmission.Indian J Gastroenterol. 2019;66-71.
Rajamoorthy Y, Taib NM, Munusamy S, Anwar S, Wagner AL, Mudatsir M,Khin AA. Knowledge and awareness of hepatitis B among households in Malaysia: a community-based cross-sectional survey. BMC Public Health. 2019;19(1):47.
Dortey BA, Anaba EA, Lassey AT, Damale NKR, Maya ET. Seroprevalence of Hepatitis B virus infection and associated factors among pregnant women at Korle-Bu Teaching Hospital, Ghana. PlosOne. 2020;15(4):e0232208.
Fattovich G, Bortolotti F, Donato F. Natural history of chronic hepatitis B: special emphasis on disease progression and prognostic factors. Journal of Hepatology. 2008;48(2):335-352.
Patel PH, Nerurkar AB, Patel MR. Seroprevalence of Hepatitis B Surface Antigen in patients attending a tertiary care hospital Valsad, South Gujarat, India. Int J Med Microbiol Trop Dis. 2016;2(3):103-6.
Murhekar MV, Murhekar KM, Sehgal SC. Epidemiology of hepatitis B virus infection among the tribes of Andaman and Nicobar Islands, India. Transactions of the Royal Society of Tropical Medicine and Hygiene. 2008;102(8):729-734.
Dwivedi M, Misra SP, Misra V, Pandey A, Pant S, Singh R, Verma M. Seroprevalence of hepatitis B infection during pregnancy and risk of perinatal transmission. Indian Journal of Gastroenterology. 2011;30(2):66.
Pande C, Sarin SK, Patra S, Bhutia K, Mishra SK, Pahuja S, Mukhopadhyay CK. Prevalence, risk factors and virological profile of chronic hepatitis B virus infection in pregnant women in India. Journal of Medical Virology. 2011;83(6):962-967.
Yuen MF, Ahn SH, Lee KS, Um SH, Cho M, Yoon SK, Lee J. Two-year treatment outcome of chronic hepatitis B infection treated with besifovir vs. entecavir: results from a multicentre study. Journal of Hepatology. 20156;62(3):526-532.
World Health Organization. Global hepatitis report 2017. World Health Organization; 2017.
World Health Organization. Combating hepatitis B and C to reach elimination by 2030; 2018.
Mokaya J, McNaughton AL, Hadley MJ, Beloukas A, Geretti AM, Goedhals D, Matthews PC. A systematic review of hepatitis B virus (HBV) drug and vaccine escape mutations in Africa: A call for urgent action. PLoSNeglected Tropical Diseases. 2018;12(8):e0006629.
Sajeeth MP. Comparision of Fibrometer Test with Fibroscan and Its Correlation with Liver Biopsy in Detecting Liver Fibrosis in Patients with Hepatitis B Infection(Doctoral dissertation, Kilpauk Medical College, Chennai); 2015.
Pereira LM, Martelli CM, Merchán-Hamann E, Montarroyos UR, Braga MC, de Lima ML, Moreira RC. Population-based multicentric survey of hepatitis B infection and risk factor differences among three regions in Brazil. The American Journal of Tropical Medicine and Hygiene. 2009;81(2):240-247.
GM K. Noble S. Recombinant hepatitis B vaccine (Engerix-B) areview of its immunogenicity and protective efficacy against hepatitis B [Z]. Drugs. 2003;63(10):1021-51.
Kumar A, Kumar SI, Pandey R, Naik S, Aggarwal R. Hepatitis B virus genotype A is more often associated with severe liver disease in northern India than is genotype D; 2005.
Current Updates on Diagnostic Methods available for COVID-19 Infection. Poojakumari Vinay Shukla and Vijay J Upadhye. Uttar Pradesh Journal of Zoology. 2020;41(9):36-46.
Current Updates on Diagnostics for Hepatitis B Infection. Pallavikachhawah and Dr. Vijay upadhye. Tathapi (UGC Care Journal).2020;19(19). ISSN: 2320-0693.