In vitro ANTI-OXIDANT AND ANTI-CANCER EFFICACY OF SILVER NANOPARTICLES SYNTHESIZED FROM THE SEAWEED Syringodium isoetifolium (D.) (1939) COLLECTED FROM THE PULICAT LAKE OF TAMIL NADU
L. JAYALAKSHMI
Department of Advanced Zoology and Biotechnology, Guru Nanak College, Chennai 600042, India.
J. GOMATHY
Department of Advanced Zoology and Biotechnology, Guru Nanak College, Chennai 600042, India.
J. JAYANTHI
Department of Advanced Zoology and Biotechnology, Guru Nanak College, Chennai 600042, India.
M. G. RAGUNATHAN
Department of Advanced Zoology and Biotechnology, Guru Nanak College, Chennai 600042, India.
*Author to whom correspondence should be addressed.
Abstract
Seaweed is a natural, renewable and much unexplored marine resource, which are capable and reliable sources in the field of pharmaceuticals and drug discovery. The seaweed, Syringodium isoetifolium is our target plant for the study, which was collected from the Pulicat lake of Tamil Nadu. The obtained seaweeds were processed and the silver nanoparticles were synthesized from the aqueous extract of the plant material. The formation of silver nanoparticles was characterized using the UV visible spectroscopy, Scanning Electron Microscope (SEM) and Fourier Transform Infrared Spectroscopy (FTIR). After the characteristic confirmation, the biosynthesized nanoparticles were evaluated for its antioxidant potential using various appropriate assays (DPPH, FRAP and ABTS), also the anti-proliferative efficacy of the same was determined using MTT assay against cancerous cell lines (COLO 320 and MCF-7).
Keywords: Syringodium isoetifolium, silver nanoparticles, anti-oxidant activity and anti-cancer activity