A Review on Scianna Blood Group System

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Published: 2023-08-07

DOI: 10.56557/upjoz/2023/v44i173590

Page: 33-36


M. S. Bhosale

Department of Forensic Biology, Institute of Forensic Science, Mumbai-400032, India.

S. A. Kawade *

R. B. Narayanrao Borawake College, Shrirampur, Dist. Ahmednagar-413709, M.S., India.

*Author to whom correspondence should be addressed.


Abstract

The Scianna blood group system consists of seven antigens expressed on erythrocyte membrane-associated protein (ERMAP) which is encoded by the gene present on the short arm of chromosome 1 at 1p36.2-p22.1 locus which is close to but distinct from Rh locus. The 475 amino acid ERMAP glycoprotein belongs to immunoglobulin superfamily containing a single IgSF domain. It is highly expressed in erythroid tissues. The antibodies of Scianna blood group are clinically less significant. ERMAP glycoprotein is thought to be involved in cell adhesion/receptor, immune recognition and signal transduction.

Keywords: Scianna blood group, ERMAP glycoprotein, IgSF superfamily, erythroid tissues, cell adhesion-receptor


How to Cite

Bhosale , M. S., & Kawade , S. A. (2023). A Review on Scianna Blood Group System. UTTAR PRADESH JOURNAL OF ZOOLOGY, 44(17), 33–36. https://doi.org/10.56557/upjoz/2023/v44i173590

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