Evaluation of Analgesic Property of Drynaria quercifolia Rhizome Extract
R. Jagatheeswari *
PG & Research Department of Biochemistry, Sengamala Thayaar Educational Trust Women’s College (Autonomous), (Affiliated to Bharathidasan University), Sundarakkottai, Mannargudi-614 016, Thiruvarur (Dt.), Tamil Nadu, India.
G. Prasanna
PG & Research Department of Biochemistry, Sengamala Thayaar Educational Trust Women’s College (Autonomous), (Affiliated to Bharathidasan University), Sundarakkottai, Mannargudi-614 016, Thiruvarur (Dt.), Tamil Nadu, India.
*Author to whom correspondence should be addressed.
Abstract
Analgesics are drugs that primarily relieve pain. The main class of painkillers is narcotics, which include additional drugs that are chemically based on morphine molecules. Phytochemicals are a more recent evolution of the term that highlights most of the plant sources of these protective and preventive compounds. Many herbal preparations are prescribed as analgesics in the traditional literature. The search for new analgesics from a large number of medicinal plant resources is intensifying. In this study, we performed a phytochemical screening and analgesic activity of the bark of Drynaria quercifolia. Phytochemicals have shown that the presence of terpenoids in flavonoids, phenols, saponins, glycosides, alkaloids, polyphenols, proteins, triterpenoids, bark of Drynaria quercifolia has been proven as analgesic activity. Drynaria quercifolia has strong analgesic properties mediated by peripheral and central inhibitory mechanisms. The potential mechanism of action of Drynaria quercifolia may be due to the synergistic action of the phytochemicals present in it. This can provide a justification for the use of this plant in pain and inflammatory diseases in natural medicine.
Keywords: Analgesic activity, medicinal plants, phytochemical, methanolic extract, Drynaria quercifolia