Therapeutic Management of Canine Ehrlichiosis: Lesson Learned from Bareilly, India

Rashmi Mishra

Division of Veterinary Parasitology, ICAR-Indian Veterinary Research Institute, Izatnagar, Bareilly, Uttar Pradesh, India.

Pashupathi M *

Division of Biochemistry, ICAR-Indian Veterinary Research Institute, Izatnagar, Bareilly, Uttar Pradesh, India.

Priyanka Pal

Division of Veterinary Surgery and Radiology, NDVSU, Jabalpur, Madhya Pradesh, India.

Harshit Saxena

Division of Veterinary Medicine, ICAR-Indian Veterinary Research Institute, Izatnagar, Bareilly, Uttar Pradesh, India.

DS Kumara Wodeyar

Department of VPB, Veterinary College, Gadag, Karnataka, India.

Sakshi

Division of Veterinary Medicine, ICAR-Indian Veterinary Research Institute, Izatnagar, Bareilly, Uttar Pradesh, India.

Divyaprakash

Division of Biochemistry, ICAR-Indian Veterinary Research Institute, Izatnagar, Bareilly, Uttar Pradesh, India.

Priyanshi Yadav

Division of Veterinary Microbiology, ICAR-Indian Veterinary Research Institute, Izatnagar, Bareilly, Uttar Pradesh, India.

Priyanka Yadav

Division of Veterinary Microbiology, ICAR-Indian Veterinary Research Institute, Izatnagar, Bareilly, Uttar Pradesh, India.

*Author to whom correspondence should be addressed.


Abstract

The study was conducted on 5 dogs presented at Teaching Veterinary Clinical Complex, Indian Veterinary Research Institute with history of anorexia, lethargy, weakness, high fever, vomiting, severe panting and heavy tick infestation. Physical examination of dogs revealed increased respiratory rate, pale mucus membrane and conjunctiva, dehydration and enlarged lymph nodes. Haematological finding showed marked anaemia and thrombocytopenia. Sonographic and radiographic investigation of the abdomen revealed splenomegaly and partial hepatomegaly. Parasitological examination found it positive for Ehrlichia canis and confirmed the ticks Rhipicephalus sanguineus. Dog was treated with doxycycline @ 10 mg/kg for 28 days in divided dose with supportive therapy. Dog showed marked recovery after 2 dose of doxycycline and re-examination of blood after 20 days gave negative results in rapid test kit.

Keywords: Ehrlichia canis, anaemia, splenomegaly, Rhipicephalus sanguineus, thrombocytopenia doxycycline


How to Cite

Mishra , R., Pashupathi M, Pal , P., Saxena , H., Wodeyar , D. K., Sakshi, Divyaprakash, Yadav , P., & Yadav , P. (2024). Therapeutic Management of Canine Ehrlichiosis: Lesson Learned from Bareilly, India. UTTAR PRADESH JOURNAL OF ZOOLOGY, 45(7), 178–183. https://doi.org/10.56557/upjoz/2024/v45i73991

Downloads

Download data is not yet available.

References

Dubie T, Mohammed Y, Terefe G, Muktar Y, Tesfaye J. An insight review on canine ehrlichiosis with emphasis on its epidemiology and pathogenesity importance. Global Journal of Veterinary Medicine and Research. 2014;2(4):59-67.

Asmita Shrestha and Rockson Karmacharya. Ehrlichiosis in a dog: A case study. International Journal of Veterinary Sciences and Animal Husbandry. 2016;1(5):20-23

Shrestha MN, Shrestha RD, Sharma BK. Canine Ehrlichiosis: A Case Report. Green Field. 2005;3(2).

Barman D, Baishya BC, Sarma D, Phukan A, Dutta TC. A case report of canine Ehrlichia infection in a labrador dog and its therapeutic management. Bangladesh Journal of Veterinary Medicine. 2014;12(2):237-239.

Dhankar S, Sharma RD, Jindal N. Some epidemiological observations on canine ehrlichiosis in Haryana and Delhi states. Haryana Veterinarian. 2011;50:9-14.

Singla LD, Singh H, Kaur P, Singh ND, Singh NK, Juyal PD. Serodetection of Ehrlichia canis infection in dogs from Ludhiana district of Punjab, India. Journal of Parasitic Diseases. 2011;35:195-198.

Das M, Konar S. Clinical and hematological study of canine Ehrlichiosis with other hemoprotozoan parasites in Kolkata, West Bengal, India. Asian Pacific Journal of Tropical Biomedicine. 2013;3(11):913-915.

Bhadesiya CM, Raval SK. Hematobiochemical changes in ehrlichiosis in dogs of Anand region, Gujarat. Veterinary World. 2015;8(6):713-717.

Kasondra A, Gupta S, Bhai GABB, Saini VK. Therapeutic management of canine ehrlichiosis with aid of blood transfusion: A case report. Journal of Parasitic Diseases. 2017;41:395-397.

Phuyal S, Jha VC, Subedi M. Prevalence of blood parasites in dogs of Kathmandu Valley. Nepalese Veterinary Journal. 2017;34:107-112.

Nair AD, Cheng C, Ganta CK, Sanderson MW, Alleman AR, Munderloh UG, Ganta RR. Comparative experimental infection study in dogs with Ehrlichia canis, E. chaffeensis, Anaplasma platys and A. phagocytophilum. PLoS One. 2016;11(2): e0148239.

Shrestha A, Karmacharya R. Ehrlichiosis in a dog: A case study. International Journal of Veterinary Sciences and Animal Husbandry. 2016;1(5):20-23.

Zhang X, Luo T, Keysary A, Baneth G, Miyashiro S, Strenger C, Waner T, McBride JW. Genetic and antigenic diversities of major immunoreactive proteins in globally distributed Ehrlichia canis strains. Clinical and Vaccine Immunology. 2008;15(7):1080-1088.

Brouqui P, Davoust B, Haddad S, Vidor E, Raoult D. Serological evaluation of Ehrlichia canis infections in military dogs in Africa and Reunion Island. Veterinary Microbiology. 1991;26(1-2):103-105.

Adawa DAY, Hassan AZ, Abdullah SU, Ogunkoya AB, Adeyanju JB, Okoro, J.E. Clinical trial of long‐acting oxytetracycline and piroxicam in the treatment of canine ehrlichosis. Veterinary Quarterly. 1992;14(3):118-120.

Gahalot SC, Meena DS, Singh R, Singh YP, Mali MM, Bargurjar J, Jeph N, Meena S. Therapeutic management of canine ehrlichiosis in a german shepherd bitch: A case report. Res. J. Vet. Pract. 2017;5(4):37-39.

Kuttler KL. Chemotherapy of babesiosis. In Babesiosis of domestic animals and man. CRC Press. 2018;227-244.

Sainz Á, Roura X, Miró G, Estrada-Peña A, Kohn B, Harrus S, Solano-Gallego L. Guideline for veterinary practitioners on canine ehrlichiosis and anaplasmosis in Europe. Parasites & vectors. 2015; 8:1-20.

Chandrakant BA, Shukla RM, Rathore G, Chaudhary S, Tanwar C, Arif SA, Yadav I. Ehrlichia canis infection in a labrador retriever dog: A case report. Uttar Pradesh Journal of Zoology. 45(4):51–54. DOI: 10.56557/upjoz/2024/v45i43905