Zinc Oxide Nanoparticles from Marine Actinomycetes and its Antimicrobial Application

Nisha R.I. *

Centre for Marine Science and Technology (CMST), Manonmaniam Sundaranar University, Rajakkamangalam Kanyakumari District- 629502, Tamil Nadu, India.

Samuel Gnana Prakash Vincent

Centre for Marine Science and Technology (CMST), Manonmaniam Sundaranar University, Rajakkamangalam Kanyakumari District- 629502, Tamil Nadu, India.

*Author to whom correspondence should be addressed.


Abstract

The aim of the study is to biosynthesize and characterize Zinc oxide nanoparticles (ZnO-NPs) and to evaluate their antibacterial potential. Several isolates of the actinomycetes strain were isolated from marine sediments, and the strain was morphologically identified as actinomycetes and screened for ZnO-NPs synthesis. N5 strain showed potent activity while screening against human pathogens and further ZnO-NPs were synthesized for anti-bacterial studies. The ZnO-NPs were characterized using physio-chemical techniques such as ultraviolet spectroscopy, Fourier- Transform Infrared spectroscopy (FTIR), and X-Ray diffraction (XRD). The morphology of ZnO-NPs was analyzed using Scanning Electron Microscopy (SEM)and revealed cubic shaped. The synthesized ZnO-NPs were subjected for their antibacterial potential against human pathogens of both gram-positive and negative bacteria, using the agar well diffusion method. The ZnO-NPs showed positive results on both pathogens, Staphylococcus showed higher activity, followed by E. coli. The synthesized ZnO-NPs have good antibacterial activity which pay way to develope new antimicrobial compounds in pharmaceutical sectors.

Keywords: Zinc oxide, nanoparticles, antimicrobial, actinomycetes, pathogens, marine


How to Cite

R.I., Nisha, and Samuel Gnana Prakash Vincent. 2024. “Zinc Oxide Nanoparticles from Marine Actinomycetes and Its Antimicrobial Application”. UTTAR PRADESH JOURNAL OF ZOOLOGY 45 (18):577-87. https://doi.org/10.56557/upjoz/2024/v45i184475.