Evaluation of the Renal Protective Effects of Cyperus at Varying Concentrations in a Rat Model of Kidney Disorders
Lobna Saad Mohammed Abd Elmeged *
Department of Nutrition, Faculty of Applied, AL-Baha University, Saudi Arabia and Department of Nutrition and Food Sciences, Faculty of Home Economics, Menoufia University, Shibin el Kom, Menofia Governorate 6131567, Egypt.
Abdullah A. A. Alghamdi
Department of Biology, Faculty of Science, Al-Baha University, Al-Baha, Saudi Arabia.
*Author to whom correspondence should be addressed.
Abstract
Cyperus plants are frequently utilized around the globe to cure a range of human ailments, including as stomach and intestinal issues, as well as for their diuretic, digestant, and lactodepurant properties. Cyperus is a very promising genus in the Cyperaceae family that is used for health supplementation. So current study aims to improving kidney health using different concentrations of (Cyperus) plant in kidney disorders rats. The experiment was conducted at an animal house. all rats were provided with a standard diet for a duration of one week. Subsequently, the rats were segregated into five groups, each consisting of 6 rats. The first group, serving as the control negative (n=6) and labeled as C-ve, were exclusively fed the basal diet for a duration of 28 days. Thirty rats were administered gentamicin to induce renal problems. The experimental groups were administered different concentrations of Cyperus (5%, 7%, and 15%). The findings indicated that group 5, consisting of rats with renal disorders that were fed with 15% Cyperus powder, had the highest blood glucose levels. Conversely, there were no significant variations seen in HDL levels among group 3 & group 4. While results found that Cyperus significantly reduced in urea and uric acid in kidney disorders rats. The results suggested to use Cyperus powder for kidney disorders rats.
Keywords: Cyperus, kidney disorders, kidney health