Evaluating the Antihyperglycemic Effects of Elnabk Fruit Powder in Hyperglycemic Rats
Magbolah Salem Helal Alzahrani
Biology Department, Faculty of Science, AL-Baha University, Saudi Arabia.
Lobna Saad Mohammed Abd Elmeged *
Department of Nutrition, AL-Baha University, AlMakhwa, Saudi Arabia and Department of Nutrition and Food Sciences, Faculty of Home Economics, Menoufia University, Shibin el Kom, Menofia Governorate 6131567, Egypt.
Marwa A. Ahmed
Department of Food Sciences and Nutrition, College of Sciences, University of Bisha, P.B. 551, Bisha, 61922, Saudi Arabia.
*Author to whom correspondence should be addressed.
Abstract
Diabetes is a major public health concern that leads to significant illness, death, and long-term effects. The research involved twenty-four (24) Sprague-Dawley male albino rats, with an average weight of 150 ± 10 g. The researchers fed the rats a basic diet for one week prior to the research. The researchers then separated the rats into four groups, each containing six rats. The control group consisted of normal rats without any experimental manipulation (C–ve). The initial group, referred to as the -ve control group, comprised healthy rats who received only the basal diet for a period of twenty-eight days. The remaining rats (n = 18) with diabetes received Alloxan at a dosage of 150 mg/kg. The second group, known as the positive control group, involved diabetic rats who did not receive any food from the experimental plant. We injected alloxan into the other two experimental groups, and fed each group a basic meal of elnabk fruit at concentrations ranging from 5% to 10%. Elnabk fruit powder for 28 days. We took a blood sample at the end of the experiment, removed the organs, & subjected them to biochemical analysis. The consequences demonstrated that group 4 ( rats with diabetes fed on ten percent elnabk fruit powder) had the best serum (HDL c) when in contrast to the control positive group.
Keywords: Elnabk fruit, diabetic patients, biochemical changes