EVALUATION OF ANTIMICROBIAL ACTIVITY Dictyota dichotoma AND CuONPs AGAINST DIABETIC FOOT ULCER CAUSING MICROBES
K. GANESAN *
Department of Zoology, Nehru Memorial College (Autonomous), Affiliated Bharathidasan University, Puthanampatti, Tiruchirappalli, Tamil Nadu, India.
A. BOOPATHY RAJA
Department of Zoology, Nehru Memorial College (Autonomous), Affiliated Bharathidasan University, Puthanampatti, Tiruchirappalli, Tamil Nadu, India.
*Author to whom correspondence should be addressed.
Abstract
Bacterial infections are a major cause of chronic infections and mortality. Antibiotics have been the preferred treatment method for bacterial infections because of their cost-effectiveness and powerful outcomes. Nanoparticles (NPs) are increasingly used to target bacteria as an alternative to antibiotics. NPS is therefore regarded as next-generation antibiotics. Copper oxide (CuO) nanoparticles were investigated with potential antimicrobial applications against diabetic foot ulcer-causing microbes. All the tested samples including Copper acetate, Seaweed extract and CuONPs (B/C) showed different degrees of activities against diabetic foot ulcer-causing pathogens. Biologically synthesized CuONPs showed excellent antimicrobial activity against foot ulcer-causing microbes strains like Staphylococcus aureus, Klebsiella pneumonia, Pseudomonas aeruginosa, Escherichia coli and Proteus vulgaris.
Keywords: Dictyota dichotoma, antimicrobial, Staphylococcus aureus, Klebsiella pneumonia, Pseudomonas aeruginosa, Escherichia coli, Proteus vulgaris