EFFECT OF BROMOCRIPTINE IN DIABETES MELLITUS: A REVIEW
K. M. SARAVANAN
Research and Publication Wing, Bharath Institute of Higher Education and Research, Selaiyur, Chennai - 600 073, India.
K. MEENAKSHI SUNDARAM *
Research and Publication Wing, Bharath Institute of Higher Education and Research, Selaiyur, Chennai - 600 073, India.
*Author to whom correspondence should be addressed.
Abstract
Bromocriptine, an antinociceptive D2 receptor agonist, is thought to reorganize an excessively heightened hypothalamic drive for higher fatty acids, plasma glucose, and tri-glycerides in insulin resistant individuals by acting on circadian neuronal activity in the hypothalamus. In May 2009, the bromocriptine mesylate is officially authorized for the cure of people with diabetes. Due to its novel mechanism of action, lower rates of cardiovascular events and good side effect profile it makes an appealing choice for diabetes cure.
Keywords: Bromocriptine, drug interactions, agonist, antagonist